First, we found support for chick physiology to be influenced by hydrology variables such as water depths. Water managers have the potential to regulate the hydrology throughout much of the Everglades through a system of canals, levees, and pumps, theoretically allowing them to adjust water depths for wading birds. This hydrology variable has also been previously linked to pre-breeding adult physiological condition, nesting success, and foraging site selection of egrets and ibises. Optimal water depths for foraging wading birds differ by species, foraging strategies, and years depending on prey biomass conditions; however maintaining water depths between 2 22 and 21 cm has been suggested to provide suitable foraging conditions for both species and foraging groups. We also found that current levels of Hg exposure in the Everglades may influence the expression of heat shock proteins in egrets. This understanding may be relevant to future patterns of wading bird nesting because there are portions of the Everglades that still contain high levels of Hg in prey species of wading birds. The prevalence of chronic kidney disease continues to increase worldwide, and the relationship between renal impairment and risk of coronary artery disease is well established. RI is associated with a higher prevalence of coexisting cardiac risk factors, particularly diabetes mellitus. Patients with RI typically present with advanced and more complex coronary artery disease compared to patients without RI, as indicated by a higher proportion of multivessel disease, left main disease, ostial lesions, heavily calcified lesions, and lesions located in vein grafts. Noteworthy, cardiovascular disease accounts for over 50% of mortality among patients with chronic kidney disease before reaching end-stage renal disease. RI has consistently been shown to adversely impact prognosis among patients undergoing percutaneous coronary interventions by means of balloon angioplasty or bare metal stents. Patients with RI have been found at increased risk for death, myocardial infarction, and restenosis after bare metal stent implantation compared with patients without RI. The advent of drug-eluting stents has improved clinical and angiographic outcomes in most patient and lesion subsets. However, data on DES implantation in patients with RI remain scarce. Available reports are limited to registry-based series of patients treated with bare-metal stents or DES, to observational studies including specific patients subsets, and to post-hoc analyses of randomized trials including patients with relatively simple baseline clinical and angiographic characteristics. Previous reports of patients with RI undergoing DES implantation have observed an increased risk of mortality and myocardial infarction compared with patients without RI. DES appear to mitigate the risk of restenosis among patients with RI, although it remains a matter of debate whether the risk is similar to patients without renal impairment. Moreover, the impact of RI on the risk of stent thrombosis after DES implantation is BI-D1870 controversial.