Our results overcome these methodological caveats and confirm that there is a strong inverse association between medication Voriconazole adherence and poor control, with patients who are poorly adherent to their OAMs being nearly three times more likely to have poor glycemic control than patients who are adherent. Prominent subgroups most vulnerable for poor glucose control in our study were Ginsenoside-Rh3 younger patients and those with longer duration of diabetes. A study that examined the causes of poor glucose control and tested for the mixed effects of age obtained similar findings, but failed to show a statistically significant association between age and poor glucose control. Two other studies also showed a positive association between younger age and poor glucose control, but neither assessed whether poor medication adherence had a role in explaining this association. We evaluated the role of medication adherence in our model and found that it was a strong mediator of poor glycemic control among younger individuals with diabetes. A recent study in the United States reported poorer rates of medication adherence among lower age groups; however, these were not evaluated in a multivariate model and were based on self-reported adherence levels. Furthermore, when calculating the attributable fraction, we observed that a greater proportion of poorly controlled younger diabetes patients, compared to older age groups, could be prevented if they would be at least 80% adherent to their OAMs. Longer disease duration has also been reported in a number of studies as an independent predictor of poor glycemic control among diabetes patients; yet, again, none of these studies investigated the role of medication adherence in this association. Our results confirm that patients with disease duration of more than five years are at greater risk of poor glycemic control compared to those with shorter duration of illness. Higher risk of poor control exists even though the longer disease duration patients are more likely to have improved medication adherence, an independent factor inversely associated with poor control.