We hypothesize that with the same metabolomic environment, individuals sharing the TT genotype of the rs10492025 polymorphism seems to have a higher risk, and those with the CC genotype of the rs4359 polymorphism partially protected from the development of microalbuminuria in the presence of hypertension and or diabetes. The study was performed in subjects representative of the general population from an area with a low rate of external admission. In this population, the prevalence of microalbuminuria was in agreement with other population-based studies. Loss of genetic variation in wild populations is often associated with increased extinction risk due to reduced individual fitness and weakened resistance to natural and anthropogenic disturbances. Genetic information can be valuable in designing conservation breeding, GZD824 managing reintroductions, defining conservation units, determining conservation priorities, and evaluation of conservation effectiveness. Therefore, genetic monitoring of wild populations has increasingly become an integrated component of conservation and management of endangered species. Its suitable habitat, the limestone hills in patchy distribution. Thus, finding a novel functional gene and analyzing its role in spermatogenesis will contribute to understanding the complicated mechanisms involved in spermatogenesis and elucidating the causes of male infertility. In our study, Nkapl-deleted mices owed typical maturation arrest at meiosis. Therefore, the possibility that genetic mutations or polymorphisms in human NKAPL are associated with human male infertility is being examined. Genetic diversity plays acritical role in ecological adaptation and long-term survival of a species.