{"id":1199,"date":"2020-07-16T15:06:11","date_gmt":"2020-07-16T06:06:11","guid":{"rendered":"http:\/\/mapkinhibitorlibrary.com\/?p=1199"},"modified":"2022-01-17T11:34:35","modified_gmt":"2022-01-17T02:34:35","slug":"increasing-body-evidence-supports-preventive-role-diets-development-obesity","status":"publish","type":"post","link":"http:\/\/mapkinhibitorlibrary.com\/index.php\/2020\/07\/16\/increasing-body-evidence-supports-preventive-role-diets-development-obesity\/","title":{"rendered":"An increasing body of evidence supports a preventive role of diets against development of obesity"},"content":{"rendered":"

Moreover, HP intake induces higher postprandial thermogenesis than high-carbohydrate ingestion does. It is likely that both reduced energy intake and elevated thermogenesis might be underlying mechanisms explaining, at least in part, the reduction in body mass observed in mice and humans by replacing carbohydrates with protein. Despite the known effects of LP and HP diets on thermogenesis, limited information exists on whether varying protein sources affect body mass and composition differently. From studies in rodents, we know that consumption of hydrolyzed rather than intact proteins reduces body mass gain, adipose tissue mass and hepatic and plasma lipid concentrations. Moreover, whey ingestion decreased fat mass relative to casein intake in mice, and an intervention study with free-living overweight and obese subjects indicated that intake of whey protein, but not soy protein resulted in a significant reduction in body mass, fat mass and waist circumference, relative to the carbohydrate control treatment. In a randomized, double-blinded intervention study with cross-over design, ingestion of a liquid test meal consisting of 50% whey protein, 40% carbohydrate and 10% fat, Wortmannin 19545-26-7<\/a> induced a higher postprandial thermic effect than equal amounts of casein and soy protein. Thus, studies in both rodents and humans indicate that different protein sources might affect body weight gain and adiposity differently. The average protein intake in humans has been estimated to be 15\u201316 energy percent both in the US and in the UK. We have recently shown that obesity-prone C57BL\/6J mice exhibited distinct metabolic responses to intake of various dietary protein sources, given as 15 E% protein in a high-fat background-diet. Mice fed scallop muscle as the sole protein source were protected against diet-induced obesity, enlarged liver mass and hyperlipidemia as compared to mice fed chicken or cod filets. However, the scallop fed mice also had lower ad libitum feed intake, suggesting different satiating effects of the protein sources. Therefore, the present study was undertaken in order to elucidate whether the protein sources casein, chicken breast filet or a mixture of cod filet and scallop muscle, would affect diet-induced obesity during equal energy intake in HF diets fed to male C57BL\/6J mice for seven weeks. Furthermore, to evaluate instant differences in metabolism independent of the development of obesity indirect calorimetry was performed during the first 72 h of feeding on the HF diets containing protein from different sources. Protein from different sources at normal level was found to modulate energy balance in C57BL\/6J mice, and consumption of a cod\/scallop-mixture prevented HF diet-induced development of obesity compared to chicken and preserved glucose tolerance compared to casein. Less is known as to whether different protein sources consumed at normal dietary levels may differently affect energy balance. In the present study, we fed obesity-prone male C57BL\/6J mice HF diets with either casein, chicken filet or a mixture of cod filet and scallop muscle as the protein source.<\/p>\n","protected":false},"excerpt":{"rendered":"

Moreover, HP intake induces higher postprandial thermogenesis than high-carbohydrate ingestion does. It is likely that both reduced energy intake and elevated thermogenesis might be underlying mechanisms explaining, at least in part, the reduction in body mass observed in mice and humans by replacing carbohydrates with protein. Despite the known effects of LP and HP diets … Continue reading An increasing body of evidence supports a preventive role of diets against development of obesity<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/posts\/1199"}],"collection":[{"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/comments?post=1199"}],"version-history":[{"count":1,"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/posts\/1199\/revisions"}],"predecessor-version":[{"id":1200,"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/posts\/1199\/revisions\/1200"}],"wp:attachment":[{"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/media?parent=1199"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/categories?post=1199"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/mapkinhibitorlibrary.com\/index.php\/wp-json\/wp\/v2\/tags?post=1199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}